research highlights
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New anti-cancer agent, highly potent against chemo-resistant cancer has been characterized by IISER-TVM scientists
Development of drug resistance is a major obstacle against successful chemotherapy of many currently-used anticancer drugs in clinics as the resistance often leads to recurrence of the disease. CIL-102, a plant (Zanthoxylum simulans) derived alkaloid is highly potent against multi-drug resistant cancer. We have identified the cellular target of CIL-102 and unraveled the mechanisms of [...]