Enantioselective Approach towards Isoindolinone, Lactone, and Cyclohexane ring systems

Abstract: Isoindolinones and lactones represent an important class of synthetically useful heterocyclic compounds with impressive biological activities. Similarly, chiral cyclohexane unit occurs widely in a variety of natural products exhibiting various pharmaceutical properties. Enantioselective synthesis of these chiral skeletons has long attracted extensive interest of synthetic chemists. Many synthetic strategies have been previously reported to prepare these organic molecules. In this talk, I will be delineating our efforts towards the enantioselective synthesis of such useful moieties using a tandem process.