Dr N. Sadananda Singh
Assistant Professor Grade I (Biology)
  +91 (0)471 - 2778047

1) Maillet et al., (2016) Modeling doxorubicin-induced cardiotoxicity in human pluripotent stem cell derived-acrdiomyocytes. Scientific Reports (accepted for publication)

2) Sadananda SN,  Foo J.N, Toh M.T., Cermakova L., Chan T., Liany H., Trigueros-Motos L., Singaraja R.R., Hayden, M.R., Francis G. A., Frohlich J., Khor C.C. and Brunham L.R. (2015) Targeted Next-Generation Sequencing to Diagnose Disorders of HDL Cholesterol.  J. Lipid Res (accepted)

3) Shao, N.*, Singh, N.S.*, Slade, S., Jones, A. and Balasubramanian M.K. (2015)Genetic Code Expansion in Schizosaccharomyces pombe. Scientific Reports (accepted for publication) *shared first author

4) Brunham, L.R., Kang, M.H., Van Karnebeek, C., Sadananda, S.N., Collins, J.A., Zhang, L.H., Sayson, B., Miao, F., Matthijs, G., Stockler, S., Frohlich, J., Cassiman, D., Rabkin, S.W., and Hayden, M.R. Clinical, Biochemical, and Molecular Characterization of Novel Mutations in ABCA1 in Families with Tangier Disease JIMD Reports (accepted for publication)

5) Feoktistova, A., Morrell-Falvey, J., Chen, J.S., Singh, N.S., Balasubramanian, M.K. and Gould, K.L. (2012) The fission yeast septation initiation network (SIN) kinase, Sid2, is required for SIN asymmetry and regulates the SIN scaffold, Cdc11. Mol. Biol. Cell. 23(9):1636-45.

6) Singh, N.S., Shao, N., McLean, J.R., Sevugan, M., Ren, L., Chew, T.G., Bimbo, A., Sharma, R.,Tang, X., Gould, K.L. and Balasubramanian, M.K. (2011) SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Curr Biol. 21(23):1968-78.

7) Seshadri, A., Singh, N.S. and Varshney, U. (2010) Recycling of the posttermination complexes of Mycobacterium smegmatis and Escherichia coli ribosomes using heterologous factors. J. Mol. Biol. 401(5):854-65.

8) Das, G., Thotala, D.K., Kapoor, S., Karunanithi, S., Thakur, S.S., Singh, N.S. and Varshney, U. (2008) Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli. EMBO J. 27(6):840-851.

9) Singh, N.S., Ahmed, R., Sangeetha, R. and Varshney, U. (2008) Recycling of ribosomal complexes stalled at the step of elongation in Escherichia coli. J. Mol. Biol. 380(3):451-464.

10) Kachroo, A.H., Kancherla, A.K., Singh, N.S., Varshney, U. and Mahadevan, S. (2007) Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose. Mol. Microbiol. 66(6):1382-1395.

11) Selvaraj, M., Roy, S., Singh, N.S., Sangeetha, R., Varshney, U. and Vijayan, M. (2007) Structural plasticity and enzyme action: crystal structures of Mycobacterium tuberculosis peptidyl-tRNA hydrolase. J. Mol. Biol. 372(1):186-193.

12) Selvaraj, M., Singh, N.S., Roy, S., Sangeetha, R., Varshney, U. and Vijayan, M. (2006) Cloning, expression, purification, crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Mycobacterium tuberculosis. Acta Crystallograph Sect F Struct Biol Cryst Commun. 62(9):913-915.

13) Singh, N.S., Das G, Seshadri A, Sangeetha R, Varshney U. (2005) Evidence for a role of initiation factor 3 in recycling of ribosomal complexes stalled on mRNAs in Escherichia coli. Nucleic Acids Res. 33, 5591-601.